Journal of Clinical & Experimental Dermatology Research
Open Access
ISSN: 2155-9554
ISSN: 2155-9554
Sarita Sanke, Vibhu Mendiratta and Ram Chander
Lady Hardinge Medical College, India
Posters & Accepted Abstracts: J Clin Exp Dermatol Res
Introduction: Lichen planus pigmentosus is a distinct clinical entity commonly encountered in the Indian popu-lation. Aim: To study the clinico-etiological profile of Lichen Planus Pigmentosus (LPP) at a tertiary care hospital. Methods: Hundred patients with clinically and histopathologically confirmed the diagnosis of LPP were includ-ed. Demographic details including the age of onset, duration of disease, symptoms and family history were ob-tained. History regarding any precipitating factors, cosmetics, drug intake and associated cutaneous or systemic diseases was taken. Clinical examination of the skin, oral cavity, hair and nails were carried out. Results: Of the total 100 patients, 56 (56%) were females and 44 (44%) males with age ranging from 18 to 54 years (mean age - 31.23 years). The duration of disease ranged from 2 to 60 months with a mean of 19.31 months. Cosmetic disfigurement (68%) was the commonest complaint, followed by itching (41%) while 30% of the patients were asymptomatic. History of topical mustard oil and henna/hair dye application was present in 62% and 48% of the cases each. Other topicals included perfumes (24%), aftershave lotion (36%) and cosmetics (20%). Face (54%) and neck (48%) were the commonest sites affected, followed by the upper back (36%), up-per limbs and chest (each 32%). Eleven patients showed only flexural involvement. The commonest pattern of pigmentation was diffuse (56%) followed by reticular in 16%. The color of the pigmentation varied from slate grey to brownish-black in varying proportions. A positive association was found between hypothyroidism with diffuse LPP where the p-value was <0.001. Conclusion: LPP is a distinct clinical entity caused by diverse etiological factors and shows varied clinical pat-terns. All the patients should be advised to stop using mustard oil/henna/ hair dye/ aftershave lotions and cosmet-ics. Hypothyroidism can be considered to be a disease associated with LPP and all the patients should be investi-gated for the same.
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