Journal of Clinical & Experimental Dermatology Research
Open Access
ISSN: 2155-9554
+44 1478 350008
ISSN: 2155-9554
+44 1478 350008
Arpi Avetisyan1, A Markosian1, M Petrosyan2, N Sahakyan2, A Trchounian2 and S Aloyan1
ScientificTracks Abstracts-Workshop: J Clin Exp Dermatol Res
The aim of this study was to analyze the chemical composition of essential oils from three different species of basil, O.basilicumpurpureum (Purple basil), O.basilicumthyrsiflora (Thai basil) and O.citrodorum (Lemon basil) and to test their biological activities. The three basil species were cultivated in the same field at the elevation of 1600 m above sea level in the Kotayk Region of Armenia. The essential oils were obtained by steam distillation in a Clevenger-type apparatus, a HP GC-MS setup was used to determine their chemical composition. According to the results, Purple basil essential oil contained 57.3% of methyl-chavicol (estragol); Thai basil oil had 68.0% of linalool and the main constituents of Lemon basil oil were nerol (23.0%) and citral (20.7%). The antioxidant activities of these essential oils were measured using DPPH assays. The highest antioxidant activity was demonstrated by Thai basil essential oil: IC50 value for it was equal to the standardized Grapefruit Seed Extract used as a control sample. The tyrosinase inhibition abilities of all three oils were also assessed. Obtained data indicate that basil essential oils can be useful natural agents for cosmetic applications and food dietary supplements. To test the possibilities for cosmetic application, several synergistic mixes containing essential oils from all three basil species were created and added to cosmetic cream bases. The oil mixes used in the creams were designed taking into account the dermal maximum values defined for their constituents. The creams were used for in vivo testing on volunteers.
Arpi Avetisyan is a Research Associate at Nairian CJSC, an Armenia-based all-natural cosmetics manufacturer. Her primary responsibility in the company is Technology Development for production and Scientific Research in the field of Herbal Cosmetics. She is interested in safe use of various herbs and essential oils to address diverse cosmetology issues. Before joining Nairian CJSC,She was a Researcher at the Institute of Chemical Physics of NAS of Republic of Armenia. She obtained her MS degree in Chemistry from Yerevan State University, Yerevan, Armenia.