Sitah N Alzuman
King Khaled Eye Specialist Hospital, KSA
Posters & Accepted Abstracts: J Drug Metab Toxicol
Antibiotics were considered â�?�?miracleâ�? drugs when they were presented in the middle of the 20th century. However, excessive use of antibiotics has long been a worry in the medical community-most specifically the development of antibiotic resistant especially against a systemic medicine (OR medication OR antibiotic?), but is it less problematic in ophthalmic field? Bacterial infections of the eye are common and ophthalmologists are spoilt (little harsh word) for choice with a variety of antibiotics available in the market which are mainly used topically, thereby help ophthalmologist to achieving high concentrations; often much above the Minimum Inhibitory Concentration (MIC) of antibiotics in ocular tissues during therapy. These high concentrations are effective in treating bacteria that are deemed resistance using standard interpretations of susceptibility. But the important question is whether systemic in vitro susceptibility standards accurately interpret for ocular infection as well. Until recently, ocular pathogens resistant to fluoroquinolones have been minimal but the pattern is currently alarming. Among the most common types of ocular infections, we need to know which one reflects arise in resistance. Also, if the current practice is enough to manage the ocular infection or reconsideration is required for future.