Reproductive System & Sexual Disorders: Current Research
Open Access
ISSN: 2161-038X
ISSN: 2161-038X
Laily Najafi, Mohammad E Khamseh, Maryam Kashanian, Ladan Younesi, Azadeh Abedini, Ameneh Ebrahim Valojerdi, Mojtaba Malek and Maryam Kadivar
Iran University of Medical Sciences, Iran
Alborz University of Medical Sciences, Irany
Posters & Accepted Abstracts: Reprod Syst Sex Disord
Aim: To investigate the relationship between antenatal Umbilical Coiling Index (UCI) and postnatal UCI in normal pregnant parturients and complicated with Gestational Diabetes Mellitus (GDM). Methods: This prospective study consisted of parturients that were divided into two groups (normal pregnancy and GDM). Ultrasound scan of umbilical cord was performed at 2nd and 3rd trimesters. Postnatal UCI evaluation was performed within 24 hours after delivery. Gestational diabetes was confirmed at 24â�?�?28 weeks of gestation by one-step strategy. Results: At 18â�?�?23 WG, the frequency distribution (10th, 90th percentiles, mean�?±SD) of the UCI in the GDM and normal groups were (0.13, 0.66, 0.32�?±0.19) and (0.18, 0.74, 0.4�?±0.31), respectively. These values were (0.12, 0.4, 0.25�?±0.11) in the GDM group at 37â�?�?41 WG and (0.17, 0.43, 0.29�?±0.11) in the normal group. The mean for postnatal UCI was 0.21�?±0.12 in the GDM group, and 0.21�?±0.09 in the normal pregnancy (P=0.61). Postnatal UCI was more related to antenatal UCI at 37â�?�?41 WG in both groups. A significant association at 18â�?�?23 WG was found between GDM/normal groups and UCI categorization (hypocoiling <10th, normocoiling 10thâ�?�?90th and hypercoiling >90th) (P=0.001). However, hypocoiling was significantly more frequent in GDM than normal in both antenatal evaluations (P<0.001, P=0.006). In the GDM group, a significant association was found between antenatal UCI and postnatal UCI categories (P=0.004). Conclusions: Antenatal UCI in GDM group were lower in comparison with normal pregnancy. GDM does not affect postnatal UCI. The most abnormal pattern of coiling in GDM was hypocoiling in both trimesters.
Laily Najafi is pursuing her PhD in Clinical Diabetes at Iran University of Medical Sciences. She has completed the General Physician from Shiraz University of Medical Sciences. She has published more than 20 papers in reputed journals.
Email:lailynajafi@yahoo.com