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Angioimmunoblastic T-cell lymphoma: Case report of a diagnostic c | 19887
Journal of Hematology & Thromboembolic Diseases

Journal of Hematology & Thromboembolic Diseases
Open Access

ISSN: 2329-8790

Angioimmunoblastic T-cell lymphoma: Case report of a diagnostic challenge presented as a lymphoproliferative syndrome


Joint Event on 12th International Conference on Hematology and Hematological Oncology & 6th International Conference on HIV/AIDS, STDs and STIs

October 29-30, 2018 | San Francisco, USA

Antunes Leticia Alves

Santa Casa de Sao Paulo, Brazil

Scientific Tracks Abstracts: J Hematol Thrombo Dis

Abstract :

Brazilian female patient, 51-year-old, born in the State of Bahia, rural worker, married, Catholic, was living in São Paulo for 2 months. She was admitted to the Emergency Department at Santa Casa of São Paulo in October/2014 complaining of abdominal pain, nausea, vomiting, lymphadenomegaly, fever, night sweats and weight loss (10kg) that had begun about 3 months ago. She smoked 1 pack of cigarettes per day for 36 years, however, she denied any past medical history or agrotoxic exposure. The complete blood count (CBC) showed anemia, eosinophilia, and thrombocytopenia. All the serologies for infectious diseases were negative, except for IgM EBV, that was positive. Abdominal ultrasound showed homogeneous hepatosplenomegaly, periportal lymphadenomegaly, a simple cyst in the right kidney and small amount of ascites. CT scan of the chest showed small nodules in the lungs, a small amount of pericardial effusion, increased number of lymph nodes in mediastinal, tracheal and intracranial regions, increased size of lymph nodes in hilar region bilaterally as well as in the chains of the diaphragm, clavicles, and in the axillaries chains. Myelogram ruled out Leishmaniasis. The bone marrow biopsy was only hypercellular, showing hyperplasia of the three myeloid types. Lastly, the cervical lymph node biopsy was done with immunophenotyping: CD45 diffusely positive; CD3 positive in the small and medium cells; CD20 positive in immunoblasts; CD4 positive in most of the lymphocytes; T-cell lymphoma with angioimmunoblastic features.

Biography :

Leticia Antunes has a Medical Degree from the Federal University of Sao Carlos and is a former resident in Internal Medicine from Santa Casa de Sao Paulo, Brazil. She is now applying for Medical Residency in the United States.

E-mail: le.alvesantunes@gmail.com

 

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