Journal of Physical Chemistry & Biophysics
Open Access
ISSN: 2161-0398
ISSN: 2161-0398
N F Starodub, N F Slishek and K E Shavanova
Posters-Accepted Abstracts: J Phys Chem Biophys
To overcome number of disadvantages in the existed traditional methods intended for the control of the presence mycotoxins in food and feeds, it was developed a number of approaches based on the principles of biosensorics. In particular during our investigations it was created a several optical immune biosensors based on the application of fiber optics, surface plasmon resonance (SPR), total internal reflection ellipsometry (TIRE), nano-porous silicon (nPSi), and nanorods of some metal oxides, namely such as ZnO and TiO2. In additional to it was proposed the amperometrical and potentiometrical immune biosensors, in particular, based on the cerium oxide field effect transistors (CeOFET) and nano-electrodes. The comparison of the efficiency of applications of the mentioned above developed immune biosensors is the main purpose of the report from one side and from other one to underline the preferences of the non-labeled optical devices before the electrochemical biosensors and traditional ELISA-method. It will be a special underlined that the application of nPSi as transducer allows to us recommending biosensor based on it for screening control with the application in the field conditions due to simplicity technical construction and analysis fulfillment. Moreover, it was demonstrated efficiency of the nPSi in case of creation of devices of type lab on a chip. The non-labeled SPR and, in particular, TIRE based biosensors may be effectively used for the verification of preliminary obtained results. Such types of biosensors have the sensitivity which is no less and even higher that it is for traditional approaches based on some chromatography and the ELISA methods. It will be demonstrated that the nonlabeled optical immune biosensors meet all practice requirements.