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Administration of Iranian Propolis attenuates oxidative stress an | 44785
Medicinal & Aromatic Plants

Medicinal & Aromatic Plants
Open Access

ISSN: 2167-0412

+44 1300 500008

Administration of Iranian Propolis attenuates oxidative stress and blood glucose in type II diabetic patients: a randomized, double-blind, placebo-controlled, clinical trial


5th International Conference & Exhibition on Herbal & Traditional Medicine

November 05-06, 2018 | London, UK

Sepideh Hesami

Qazvin University of Medical Science, Qazvin, Iran

Posters & Accepted Abstracts: Med Aromat Plants

Abstract :

Hyperglycemia in diabetic people resulted in oxidative conditions. Propolis is the third most important component of bee products which has various functional properties such as anti-oxidant due to its components. The aim of this study is the evaluation of Propolis effect on fructosamine level, the catalase activity, and the level of oxidized LDL changes in type 2 diabetic patients. In this double-blind, randomized controlled trial study, 62 type 2 diabetic patients, attending the Endocrine clinic in Velayat Hospital (Qazvin, Iran) in 2017, were randomly assigned to one of intervention and placebo (n =31) groups. Participants in the intervention group took propolis capsule (500 mg) 3 times a day and those in the placebo group took placebo capsules for 8-week. Fructosamine level, catalase activity and the level of oxidized-LDL were measured at the baseline and at the end of the study. Statistical analysis was performed using SPSS software. At the end of the study, significant differences were seen within and between groups. In Propolis group compared to the placebo, fructosamine (p < 0.05), and the level of oxidized LDL (p < 0.05) decreased, and catalase activity (p < 0.05) improved. However, there were no significant changes in the placebo group at the end of the trial. Eight weeks intake of Propolis as a supplement in type II diabetic patients could improve antioxidant defense and decline production of hyperglycemia-induced products such as fructosamine.

Biography :

E-mail: sp_hsm@yahoo.com

 

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