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A comprehensive health impact assessment and determinants of qual | 726
Journal of Clinical & Experimental Dermatology Research

Journal of Clinical & Experimental Dermatology Research
Open Access

ISSN: 2155-9554

+44 1478 350008

A comprehensive health impact assessment and determinants of quality of life, health and psychological status in acne patients


2nd International Conference on Clinical Research Cardiology, Ophthalmology & Dermatology

5-7 March 2012 Omaha Marriott, USA

Tabolli Stefano, Pagliarello Calogero and Di Pietro Cristina

Accepted Abstracts: J Clin Exp Dermatol Res

Abstract :

Background: Acne adversely affects all aspects of quality of life (QoL). Although many papers assessed acne-specific QoL impairment, there are few data on its impact on general health and psychological status. Apart from acne severity, little is know about determinants of a worse QoL. Objectives: Measurement of acne impact on QoL, health and psychological status. To analyse the relationship between socio-demographic variables, disease severity and mental status on QoL of acne sufferers. Methods: Acne cases were selected from a survey conducted in 2010. The Short-Form 12-Item Health Survey and the Skindex-29 were used to assess health status and QoL. The 12-Items General Health Questionnaire was used to identify individuals at risk for non-psychotic psychiatric disorders (GHQ-positive). Physician (PhGA) and patient global assessments were obtained. We investigated the variables involved in the QoL through a logistic regression analysis. Results: 195 cases were analysed. 26% were GHQ-positive, reporting an impact on health status due to acne worse respect other chronic diseases. Males rather than females reported a poorer QoL. A GHQ-positive status (Skindex-29 overall: OR 2.6;95% CI 1.20-5.60,p<0.05, functioning:OR 2.5;95% CI 1.17-5.44,p<0.05, symptoms:OR 3.0; 95% CI 1.36-6.53,p<0.01; emotions:OR 2.55; 95% CI 1.19-5.46,p<0.05) and having a severe/very severe PhGA (Skindex-29 overall:OR 3.4; 95% CI 1.20-10.38,p<0.05) were associated with a poor QoL. Age of onset >25 was linked to being GHQ-positive (OR 2.92; 95% CI 1.2-7.1, p<0.05) controlling for gender, marital status and educational level. Conclusions: Acne is not a minor disease in comparison with other chronic conditions. Age of patient is capable to influence GHQ status which in turn affects QoL.

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