CRP Levels And Leukocytes | Peer Reviewed Journals
Journal of Leukemia

Journal of Leukemia
Open Access

ISSN: 2329-6917

CRP Levels And Leukocytes

C-reactive protein (CRP), a marker of acute-phase inflammatory response, has been suggested to be useful for early detection of cancer. A recent meta-analysis using 14 prospective studies of circulating CRP and any incident cancer, comprising 3,957 cancer cases, showed that a log unit increase in CRP was associated with a 1.1-unit increase in overall cancer risk. Inflammation-associated oxidative damage could initiate carcinogenesis, which causes inactivating mutations in tumor suppressor genes or posttranslational modifications in proteins involved in DNA repair or apoptotic control.

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