Strategies for Achieving the Goals of a Lung-Protective Ventilation Protocol in Large Clinical Trials

Friedemann J. H. Taut¹, Gordana Bothe¹, Peter Schenk², Nathan Dean³, Kenneth Krell⁴, Andreas Günther⁵, James F. Lewis⁶ and Roger G. Spragg^7*

¹Nycomed GmbH, Konstanz, Germany, E-mail: rspragg@ucsd.edu

²Department of Internal Medicine III, General Hospital Vienna, Vienna, Austria, E-mail: rspragg@ucsd.edu

³Intermountain Medical Center, Murray, UT, USA, E-mail: rspragg@ucsd.edu

⁴Eastern Idaho Medical Center, Idaho Falls, ID, USA, E-mail: rspragg@ucsd.edu

⁵Department of Pulmonary and Critical Care, Justus-Liebig-University, Giessen, Germany, E-mail: rspragg@ucsd.edu

⁶St Joseph’s Health Center, University of Western Ontario, London, Ontario, Canada, E-mail: rspragg@ucsd.edu

⁷Division of Pulmonary and Critical Care Medicine, University of California San Diego, San Diego VA Healthcare System, La Jolla, CA, USA, E-mail: rspragg@ucsd.edu

^*Corresponding Author: Roger G. Spragg, MD, VA Medical Center - 151A, 3350 La Jolla Village Drive, San Diego, CA, 92161, USA, Tel: +1 858-642-1248, Fax: +1 858-552-7592 Email: