Screening RB1 Gene in Algerian Patients and Predicting the Pathogenicity of Variations by In Silico Analysis

Amina Mama Boubkeur^1*, Lotfi Louhibi¹, Meriem Abdi¹, Fatima Zohra Moghtit¹, Nacera Tabet Aoul², Rym Abderrahmane¹, Khadija Mahmoudi³, Meriem Aberkane^1,4 and Nadhira Saidi-Mehtar¹

¹Department of Applied Molecular Genetics, Laboratory of Molecular and Cellular Genetics, Faculty of Natural and Life Sciences, University of Science and Technology of Oran, Algeria

²Department of Biotechnology, University of Oran, Algeria

³Pediatric Hospital of Canastel, Department of Ophtalmology, Oran, Algeria

⁴Department of Pharmacy, Faculty of Medicine, University of Oran, 1, BP 1524 El M’naouer 31000 Oran, Algeria

^*Corresponding Author: Amina Mama Boubkeur, Department of Applied Molecular Genetics, Faculty of Natural and Life Sciences, Laboratory of Molecular and Cellular Genetics, University of Science and Technology of Oran, Mohamed Boudiaf-Ustomb-BP 1505 El, M’naouer 31000, Oran, Algeria, Tel: +213 770 50 24 01 Email: