Rapid Thinning of Retinal Nerve Fiber Layer is Predictive of a Bad Visual Prognosis of Nd4/11778 Mutation Leber Hereditary Optic Neuropathy

Lulu Wang^1#, Xin Li^1#, Yanping Xiao², Li Li², Taotao Zhang¹ and Liang Liao^2*

¹Department of Ophthalmology, Beijing University of Chinese Medicine, Beijing, China

²Department of Ophthalmology, Dongfang Hospital, Beijing University of Chinese Medicine, Beijing, China

^#Contributed equally to this work

^*Corresponding Author: Dr. Liang Liao, Department of Ophthalmology, Dongfang Hospital, Beijing University of Chinese Medicine, 1-6 Fangxingyuan, Fengtai District, Beijing 100078, China, Tel: +86 13466379490 Email:

Keywords: Leber hereditary optic neuropathy; Visual prognosis; Retinal nerve fiber layer; Mitochondrial DNA mutations; Optical coherence tomography

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