Influence of Imprinting of an X Chromosome and of the Methylene Tetrahydrofolate Reductase (MTHFR) 677C>T Polymorphism on FVIII Activity

Birgit Horvath¹, Raute Sunder-Plassmann¹, Cihan Ay², Sylvia Reitter-Pfoertner², Sylvia Kepa², Christoph Male³, Ingrid Pabinger² and Christine Mannhalter^1*

¹Department of Laboratory Medicine, Medical University of Vienna, Austria

²Division of Hematology and Hemostaseology, Department of Internal Medicine I, Medical University of Vienna, Austria

³Department of Pediatrics, Medical University of Vienna, Austria

^*Corresponding Author: Christine Mannhalter, Department of Laboratory Medicine, Medical University of Vienna, Waehringer Guertel 18-20, A-1090 Vienna, Austria, Tel: +43 664 2140745, Fax: +43 1 40400 73591 Email: