Impact of Intraoperative Ventilation with High Oxygen Content to Reduce the Incidence and Extent of Postoperative Pneumocephalus in Patients Undergoing Craniotomies

Sandhu G¹, Gonzalez-Zacarias A¹, Fiorda-Diaz J^1*, Soghomonyan S¹, Targonski D², Prevedello LM², Prevedello DM^3,4 and Bergese SD^1,4

¹Department of Anesthesiology, The Ohio State University Wexner Medical Center, Columbus, Ohio, USA

²Department of Ear, Nose and Throat, The Ohio State University Wexner Medical Center, Columbus, Ohio, USA

³Department of Neurological Surgery, The Ohio State University Wexner Medical Center, Columbus, Ohio, USA

⁴Discipline of Pharmaceutics, School of Pharmacy, University of the Western Cape, Bellville 7535, South Africa

^*Corresponding Author: Fiorda-Diaz J, The Ohio State University, Wexner Medical Center, Department Of Anesthesiology, Columbus, Ohio, USA, Tel: (614) 293-3559, Fax: (614) 366-1943 Email:

Introduction and Background