Friend of Prmt1, FOP is a Novel Component of the Nuclear SMN Complex Isolated Using Biotin Affinity Purification

Keiichi Izumikawa^1,2, Hideaki Ishikawa^1,2, Harunori Yoshikawa^1,2, Goro Terukina^1,4, Naoki Miyazawa^1,2, Hiroshi Nakayama^2,3, Yuko Nobe^2,4, Masato Taoka^2,4, Yoshio Yamauchi⁴, Sjaak Philipsen⁵, Toshiaki Isobe^2,4 and Nobuhiro Takahashi^1,2*

¹Department of Applied Biological Science, United Graduate School of Agriculture, Tokyo University of Agriculture and Technology, 3-5-8 Saiwai-cho, Fuchu, Tokyo 183- 8509, Japan

²Core Research for Evolutional Science and Technology (CREST), Japan Science and Technology Agency (JST), Sanbancho 5, Chiyoda-ku, Tokyo 102-0075, Japan

³Biomolecular Characterization Team, RIKEN Advanced Science Institute, 2-1 Hirosawa, Wako, Saitama 351-0198, Japan

⁴Department of Chemistry, Graduate School of Science, Tokyo Metropolitan University, 1-1 Minami-ohsawa, Hachioji, Tokyo 192-0397, Japan

⁵Department of Cell Biology, Erasmus MC, 3015 GE Rotterdam, The Netherlands

^*Corresponding Author: Nobuhiro Takahashi, Ph.D., Department of Applied Biological Science, Tokyo university of agriculture and technology, 3-5-8 Saiwai-cho, Fuchu, Tokyo 183-8509, Japan, Tel: 81-042-367-5709, Fax: 81-042-367-5709