Feasibility Study of Bolus 5-Fluorouracil+L-Leucovorin as Salvage Line Chemotherapy for Oral Fluorouracil-Resistant Unresectable Gastric Cancer: Hokkaido Gastrointestinal Cancer Study Group Study HGCSG1502

Yoshimitsu Kobayashi⁵, Yuh Sakata¹², Naoya Sakamoto², Michio Nakamura¹¹, Atsushi Ishiguro¹⁰, Ichiro Iwanaga⁹, Masayoshi Dazai⁸, Takahide Sasaki⁷, Kazuteru Hatanaka⁶, Takuto Miyagishima⁵, Susumu Sogabe⁵, Tetsuhito Muranaka¹, Shuhei Kawahata⁴, Kota Ono³, Satoshi Yuki², Hiroshi Nakatsumi¹, Yasuyuki Kawamoto¹, Kazuaki Harada¹, Kentaro Sawada¹, Masataka Yagisawa¹ and Yoshito Komatsu^1*

¹Cancer Center, Hokkaido University Hospital, Japan, E-mail: ykomatsu@ac.cyberhome.ne.jp

²Department of Gastroenterology and Hepatology, Hokkaido University Hospital, Japan, E-mail: ykomatsu@ac.cyberhome.ne.jp

³Clinical Research and Medical Innovation Center, Hokkaido University Hospital, Japan, E-mail: ykomatsu@ac.cyberhome.ne.jp

⁴Gastroenterology, Obihiro Kosei Hospital, Japan, E-mail: ykomatsu@ac.cyberhome.ne.jp

⁵Medical Oncology, Kushiro Rosai Hospital, Japan, E-mail: ykomatsu@ac.cyberhome.ne.jp

⁶Gastroenterology, Hakodate Municipal Hospital, Japan, E-mail: ykomatsu@ac.cyberhome.ne.jp

⁷Internal Medicine, Hokkaido Gastroenterology Hospital, Japan, E-mail: ykomatsu@ac.cyberhome.ne.jp

⁸Gastroenterology, Sapporo Medical Center NTT EC, Japan, E-mail: ykomatsu@ac.cyberhome.ne.jp

⁹Medical Oncology, Japanese Red Cross Kitami Hospital, Japan, E-mail: ykomatsu@ac.cyberhome.ne.jp

¹⁰Medical Oncology, Teine Keijinkai Hospital, Japan, E-mail: ykomatsu@ac.cyberhome.ne.jp

¹¹Gastroenterology, Sapporo City General Hospital, Japan, E-mail: ykomatsu@ac.cyberhome.ne.jp

¹²Medical Oncology, Misawa City Hospital, Japan, E-mail: ykomatsu@ac.cyberhome.ne.jp

^*Corresponding Author: Yoshito Komatsu, Cancer Center, Hokkaido University Hospital, Kita 14, Nishi 5, Kita-ku, Sapporo City, 060-0814, Hokkaido, Japan, Tel: +81-823-66-2314, Fax: +81 11706-7999 Email: