Journal of Clinical and Cellular Immunology

Journal of Clinical and Cellular Immunology
Open Access

ISSN: 2155-9899

Research Article - (2016) Volume 7, Issue 5

ER Stress-induced Inflammasome Activation Contributes to Hepatic Inflammation and Steatosis

Jinyu Zhang1,2, Kezhong Zhang3, Zihai Li1,2 and Beichu Guo1,2*
1Department of Microbiology and Immunology, Medical University of South Carolina (MUSC), Charleston, South Carolina 29425-5040, USA
2Hollings Cancer Center, Medical University of South Carolina (MUSC), Charleston, South Carolina 29425, USA
3Department of Immunology and Microbiology, Center for Molecular Medicine & Genetics, Karmanos Cancer Institute, Wayne State University School of Medicine, Detroit, MI 48201, USA
*Corresponding Author: Dr. Beichu Guo, Department of Microbiology and Immunology, Medical University of South Carolina (MUSC), Hollings Cancer Center, HO-612D, 86 Jonathan Lucas Street, Charleston, South Carolina 29425-5040, USA, Tel: 843-792-5708, Fax: (843)792-9588 Email:

Abstract