Course – Prevalence, Clinical Outcomes and Viral Shedding Patterns during Viral Respiratory Tract Infections in Intubated Intensive Care Unit–patients: Design and Protocol

Angelique ME Spoelstra–de Man⁷, Marcus J Schultz^1,2, Menno D De Jong³, Nicole P Juffermans^1,2, Tineke Winters¹, Rob BP De Wilde⁶, Monique C De Waard⁷, Kirsten D Verheul³, Peter E Spronk⁴, Frank Van Someren Gréve^1,2,3*, Sjoerd PH Rebers³, David SY Ong⁵, Richard Molenkamp³, Evert De Jonge⁶, Olaf L Cremer⁵, Annemarije Braber⁴, Jan M Binnekade¹ and Koenraad F Van Der Sluijs²

¹Department of Intensive Care, Academic Medical Center, Amsterdam, The Netherlands, E-mail: f.vansomerengreve@amc.uva.nl

²Laboratory of Experimental Intensive Care and Anesthesiology, Academic Medical Center, Amsterdam, The Netherlands, E-mail: f.vansomerengreve@amc.uva.nl

³Department of Medical Microbiology, Academic Medical Center, Amsterdam, The Netherlands, E-mail: f.vansomerengreve@amc.uva.nl

⁴Department of Intensive Care, Gelre Hospitals, Apeldoorn, The Netherlands, E-mail: f.vansomerengreve@amc.uva.nl

⁵Department of Intensive Care, University Medical Center Utrecht, Utrecht, The Netherlands, E-mail: f.vansomerengreve@amc.uva.nl

⁶Department of Intensive Care, Leiden University Medical Center, Leiden, The Netherlands, E-mail: f.vansomerengreve@amc.uva.nl

⁷Department of Intensive Care, VU Medical Center, Amsterdam, The Netherlands, E-mail: f.vansomerengreve@amc.uva.nl

^*Corresponding Author: Frank Van Someren Gréve, MD, Department of Intensive Care, Academic Medical Center, Meibergdreef 9, 1105 AZ Amsterdam, The Netherlands, Tel: +312056328 Email: