Research Director, Pharmacology and Toxicology
Narendra Vaish, Ph.D., MBA, Associate Director, Discovery Research and Pharmaceutical Development, at the RNAi and miRNA World Congress in Boston, MA.
Elimination and participation in the RNAi process. Substitution in the guide strand is intended to eliminate miRNA-like events, while preserving siRNA-like activity. Furthermore, as described previously, UsiRNAs have a lower potential for cytokine induction that can occur with standard siRNAs