Professor, Department of Physiology
Istanbul University, Turkey
He earned his Under garduation from Erzincan High school; 1975 and Bachelor’s degree from Department of Biology, Faculty of Science, Istanbul University; 1980 and done his post graduation as Master and PhD in Medical Physiology in Istanbul Faculty of Medicine, Institute of Health Sciences, Istanbul University, 1989.
He have been working on the morphology, physiology and pathology of the rat brain microvessels in experimental animal models since 1984. Starting from the beginning of the 1990’s, He focused studies on the BBB reactions to various experimental pathological conditions, especially epilepsy. In one of his articles published in “Experimental Neurology” journal in 1996, he demonstrated the conversion of a normal barrier type brain capillary into fenestrated type in an experimental setting. His research topics between 2000 and 2014 concentrated on the reactions of BBB to a number of experimental conditions including sepsis, hypertension and epilepsy. The main goal of his previous and future research is to determine putative mechanisms which may enable the treatment drugs 98% of which are unable to pass into the brain tissue owing to a functioning BBB, to permeate into the brain by physiological manipulations for opening the BBB for a desired period and subsequently closing the barrier.