James F. Leary
SVM Endowed Professor of Nanomedicine, Purdue Cancer and Birck Nanotechnology Center
Purdue University, USA
Dr. Leary is having more than 36 years in research field. His research has involved quantitative measurements of single cells (as the original inventor of high-speed flow cytometry and rare-event analysis techniques), and over the past 10 years its use in design and characterization of multi-component nanomedical systems and their interactions with cells for diagnostic and therapeutic purposes in cancer. Currently his lab and its collaborators are constructing and using multilayered dual imaging modality nanomedical systems containing superparamagnetic iron oxide cores for MRI contrast agents and also for directed in-vivo concentration of nanoparticles with chitosan natural polymer coatings containing Cy 5.5 fluorescent probes for near infrared invivo imaging and for real-time guided surgery of tumors. New projects include development of new theranostic nanomedical treatments for human ductal breast cancer combining microfluidics, 3D culture techniques and nanomedicine in “breast-on-a-chip” systems. We are also developing new in-situ PCR base nanobarcoding methods for nanotoxicity and biodistribution studies for anti-cancer nanomedical systems.
Theranostic nanomedical treatments, 3D culture techniques and nanomedicine in “breast-on-a-chip” systems and developing new in-situ PCR base nanobarcoding methods for nanotoxicity and biodistribution studies for anti-cancer nanomedical systems.