Journal of Clinical Trials
Open Access

The special issue on "The Role of Biomarkers in Shaping Future Clinical Trials" delves into the pivotal role biomarkers play in revolutionizing clinical research. Biomarkers, ranging from genetic signatures to molecular indicators, offer insights into disease mechanisms, patient stratification, and treatment response. By incorporating biomarker data into trial design, researchers can optimize patient selection, enhance treatment efficacy, and accelerate drug development. This issue explores the latest advancements, challenges, and future directions in leveraging biomarkers to drive precision medicine and improve patient outcomes in clinical trials.