Gynecology & Obstetrics

Gynecology & Obstetrics
Open Access

ISSN: 2161-0932

Zanardi A

Global Para Pharmaceutical Science, Mylan, Italy

  • Research   
    Mucoadhesive Properties of a New Intimate Hygiene Cleanser against Vulvovaginal Candidiasis
    Author(s): Benvenuti C*, Gasparri F and Zanardi A

    Objective: Performance of feminine cleansers can be improved by increasing antimicrobial potency and favouring the prolonged contact on vulvo-vaginal mucosa of active ingredients, that permits the increase of the persistence of their activity, and consequently of their efficacy. The presence of specific polymers in topical formulations allows the cleansing solution to adhere to mucosal substrates. The associations of xanthan gum with lambda carrageenan from Chondrus crispus has a high mucoadhesive potential. The aim of our study was to evaluate the mucoadhesive potential and the safety of an innovative cleanser for feminine hygiene (SA3) compared with a reference cleanser (SA) in a double-blind design. Material and Methods: The cleansers were provided at dilutions: the reference product containing thymol from Thymu.. Read More»

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