International Journal of Physical Medicine & Rehabilitation
Open Access
ISSN: 2329-9096
ISSN: 2329-9096
Department of Computer Science and Engineering, Toyohashi University of Technology, Tempaku-cho, Toyohashi, Aichi, Japan
Review Article
Exploration of Plant Based Inhibitors against SARS-CoV-2 Main Protease through Molecular Simulations: A Review
Author(s): Divya Shaji, Ryo Suzuki, Daichi Takimoto, Yuta Hashimoto, Narutoshi Tada and Noriyuki Kurita*
Coronavirus disease 2019 (COVID-19) is a pandemic first identified in China and rapidly transmitted to other countries all over the world. The lack of effective vaccines and treatments against COVID-19 causes its devastating aftermath. Therefore, it is urgently required to identify effective and safe treatments for COVID-19 and a variety of studies have been conducted for elucidating the antiviral effects of natural and plant based agents. As COVID-19 is caused by the Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2), inhibitors against SARS-CoV-2 are expected to be efficacious for the treatment of COVID-19. In this review, we will introduce the molecular simulation studies for exploring novel plant based agents as potent inhibitors against the main protease of SARS-CoV-2. These agents are expected to be utilized safely for the COVID-19 treatment... View More»
DOI:
10.35248/2329-9096.23.11.660