Anesthesia & Clinical Research
Open Access
ISSN: 2155-6148
ISSN: 2155-6148
Department of Operation, The Affiliated Hospital of Yan’an University, Shaanxi Province, China
Research Article
BIS-Guided Sedation and Prevention of Cough Reaction in Patients with General Anesthesia Caused by Extubation: A Randomised Controlled Trial
Author(s): Erfei Zhang*, Xiaoying Zhao, Xiaoyan AN, Min Wang, Jie Gao, Hailiang Zhang and Ying Li
Background: The multiple modes of SARS-CoV-2 transmission including airborne, droplet, contact, and fecal–oral transmissions that cause coronavirus disease 2019 (COVID-19) contribute to a public threat to the lives of people worldwide. Heavy aerosol production by coughing and the big peak expiratory flow during recovery from general anaesthesia in patients with respiratory infections (especially COVID-19) are the highest risk factors for infection in healthcare workers. To perform sedation before extubation significantly reduced the incidence of choking reactions during recovery from general anesthesia. However, there are few studies on endotracheal tube removal with BIS-guided sedation in PACU. We speculated that the BIS-guided sedation with dexmedetomidine and propopfol would better prevent coughing responses caused by tracheal extubation.
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DOI:
10.35248/2155-6148.22.13.1080