Endocrinology & Metabolic Syndrome
Open Access
ISSN: 2161-1017
ISSN: 2161-1017
NHS Foundation Trust, University Hospitals Birmingham, Birmingham, United Kingdom
Research Article
A Retrospective Cohort Study Evaluating the Prevalence of Vitamin D Deficiency and its Impact on the Biochemical and Clinical Presentations of Patients with Primary Hyperparathyroidism (PHPT)
Author(s): Criseno S*, Virk J, Nightingale P and Gittoes N
Background: Primary Hyperparathyroidism (PHPT) is the third most common endocrine disorder, with an estimated prevalence of 1 to 4 per 1,000 in the general population. It is well established that vitamin D deficiency co-exists with PHPT. However, there are very few studies that have compared the prevalence of vitamin D deficiency between symptomatic and asymptomatic PHPT patients.
Aim: This research evaluated the prevalence of vitamin D deficiency in patients with PHPT, and compared the prevalence of vitamin D deficiency in patients with symptomatic and asymptomatic disease.
Methods: This observational cohort study employed a retrospective design where clinical records of 400 new patients referred to the metabolic bone clinics for investigation of hypercalcaemia, between 2010 and 2017, were reviewed. The study popu.. View More»