Gynecology & Obstetrics
Open Access
ISSN: 2161-0932
ISSN: 2161-0932
Department of Medical Biochemistry and Clinical Biochemistry, (Firat Hormones Research Group), Medical School, Firat University, Elazig, 23119, Turkey
Research Article
Therapeutic Effects of Medical Ozone in the Functions and Histopathological Features of the Ovary in an Experimental Torsion-Detorsion Model
Author(s): Yakup Baykus, Rulin Deniz, Yasemen Adali, Fatih Kara, Omur Ozturk, Suna Aydin and Suleyman Aydin*
Background: Ovarian torsion is a serious gynecological condition, encountered especially during reproductive age. Medical ozone has therapeutic effects with its antioxidant, apoptotic, and anti-inflammatory properties.
Objective: This study aimed to determine the effects of medical ozone on the ovarian functions and ovarian morphology in an experimental rat ovarian torsion-detorsion model.
Methods: Twenty female Wistar albino rats were used in this study. The rats were randomized into two groups: Group 1 (torsion/detorsion+ozone) (n=10) and Group 2 (only torsion/detorsion) (n=10). Histopathological evaluation of the ovarian tissue was performed. Additionally, Total Antioxidant Capacity (TAC), Follicle-Stimulating Hormone (FSH), Estradiol (E2), and Lactate Dehydrogenase (LDH) levels were measured in the serum.
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