Gynecology & Obstetrics
Open Access
ISSN: 2161-0932
ISSN: 2161-0932
Department of Biochemistry, Kafkas University, Kars, 36100, Turkey
Research Article
Therapeutic Effects of Medical Ozone in the Functions and Histopathological Features of the Ovary in an Experimental Torsion-Detorsion Model
Author(s): Yakup Baykus, Rulin Deniz, Yasemen Adali, Fatih Kara, Omur Ozturk, Suna Aydin and Suleyman Aydin*
Background: Ovarian torsion is a serious gynecological condition, encountered especially during reproductive age. Medical ozone has therapeutic effects with its antioxidant, apoptotic, and anti-inflammatory properties.
Objective: This study aimed to determine the effects of medical ozone on the ovarian functions and ovarian morphology in an experimental rat ovarian torsion-detorsion model.
Methods: Twenty female Wistar albino rats were used in this study. The rats were randomized into two groups: Group 1 (torsion/detorsion+ozone) (n=10) and Group 2 (only torsion/detorsion) (n=10). Histopathological evaluation of the ovarian tissue was performed. Additionally, Total Antioxidant Capacity (TAC), Follicle-Stimulating Hormone (FSH), Estradiol (E2), and Lactate Dehydrogenase (LDH) levels were measured in the serum.
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