Internal Medicine
Open Access
ISSN: 2165-8048
ISSN: 2165-8048
Department of Pulmonary and Critical Care Medicine, The Fourth Affiliated Hospital of China Medical University, Shenyang, China
Research Article
Associations of Serum Cu, Zn and Se with Chronic Respiratory Diseases in the American Adults: Data from NHANES 2013?2016 and a Bidirectional Mendelian Randomization Analysis
Author(s): Hanming Yu, Taihong Lv, Zishuo Ji, Shuo Wang, Shi Liu, Yuru Chen, Qi Zhao, Li Ma and Xiu Gu*
Background: Despite studies on trace metals and Chronic Respiratory Diseases (CRDs), their causal relationship in American adults is uncertain. Our research applied observational and bidirectional Mendelian Randomization (MR) methods to ascertain this association.
Objective: The aim of this study was to evaluate the potential linkages between serum levels of Copper (Cu), Zinc (Zn) and Selenium (Se) and the incidence of chronic respiratory diseases within the adult demographic of the United States.
Methods: Drawing on the National Health and Nutrition Examination Survey (NHANES) 2013-2016 data, our study incorporated 2807 adults to examine serum Cu, Zn and Se impacts on CRDs risks using logistic regression and cubic spline analysis. Subsequently, bidirectional MR assessments were conducted to ascertain the causative.. View More»
DOI:
10.35248/2165-8048.25.15.503