Rheumatology: Current Research

Rheumatology: Current Research
Open Access

ISSN: 2161-1149 (Printed)

Sheba MF

Department of Pediatrics, Cairo University, Cairo, Egypt

  • Research Article   
    Markers for Subclinical Inflammation in Egyptian Children with Familial Mediterranean Fever: Splenomegaly and Mean Platelet Volume
    Author(s): Talaat HS, Sheba MF, Mohammed RH and Ibrahim MFM*

    Background: Familial Mediterranean fever (FMF) is an auto-inflammatory systemic disease, of an autosomal recessive inheritance, that is characterized by recurrent episodes of fever, peritonitis, pleuritis, pericarditis, and/or arthritis; MEFV is the responsible gene. Aim: To detect the correlation of Mean Platelet Volume (MPV) and splenomegaly as subclinical inflammatory markers in children with FMF at the attack-free periods. Methods: This cross-sectional study included 40 pediatric patients diagnosed clinically and according to gene mutations already with FMF and were following-up at the Rheumatology Outpatient Clinic, Children's Hospital, Cairo University. Abdominal ultrasonography was done all patients to detect splenomegaly; MPV was measured as well. Results: Patients was.. Read More»
    DOI: 10.35248/2161-1149.20.10.258

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