Journal of Antivirals & Antiretrovirals

Journal of Antivirals & Antiretrovirals
Open Access

ISSN: 1948-5964

+44 1300 500008

Satyendra Prakash

Centre of Biotechnology, University of Allahabad, Allahabad, India

  • Review Article   
    HIV Latency and Distinct Anatomical Reservoirs: A Systemic Review
    Author(s): Satyendra Prakash and Ramendra Kumar Singh*

    Although the HAART (Highly Active Antiretroviral Therapy) a triple form of drugs has exponentially enhanced the CD4+ T immune cell count in HIV-1 infected patients and has improved the expectancy of many HIV-1 infected patients’ life. The drug results have also contributed to bringing the plasma virus load up to a clinically undetectable level in HIV-1 infected patients for several years. However, with these drug interventions, complete eradication or treatment of the virus is hard to achieve. The primary obstacle that has been raised is the persistence of ongoing viral replication inside the host CD4+ T immune cells. These infected immune cells can be transformed into the latent stage (transcriptionally silent) for many years and hardly be targeted by the current HAART-based interventions. Besides this incredible specialty of the HIV-1 virus, it can also si.. View More»
    DOI: 10.35248/1948-5964.21.13.224

    Abstract HTML PDF