Journal of Developing Drugs
Open Access

Department of Pharmacology, Peking University Health Science Center, Beijing, China

Publications

• Opinion   
  The Evolving Role of Pharmacodynamics in Precision Medicine
  Author(s): Samuel Richardson*
  
  Modern medicine has made extraordinary progress in developing innovative drugs capable of treating diseases that were once considered untreatable. One patient improves rapidly, another derives only partial benefit, and a third develops significant adverse effects. While differences in drug absorption and metabolism are often discussed. I believe that pharmacodynamics the study of what drugs do to the body deserves much greater attention as a key determinant of therapeutic success. Pharmacodynamics focuses on the interaction between a drug and its biological target, including receptors, enzymes, ion channels and signaling molecules. These interactions ultimately determine whether a medicine produces the desired therapeutic effect or unintended toxicity... View More»
  

  Abstract PDF