Immunome Research
Open Access

Centre for Immunogenetics and Virology, Fundeni Clinical Institute, Bucharesct, Romania

Publications

• Review Article   
  Gastrointestinal Microbiota Impact on the Development of Food Allergy Immune Phenotype
  Author(s): Ileana Constantinescu* and Roxana Sfrent-Cornateanu
  
  Recent technological advances have allowed researchers to more accurately describe gastrointestinal microbiota composition and its interaction with the host in health and disease. Lifestyle changes, including the large-scale use of antibiotics, alter both the composition and function of the intestinal microbiome, which predisposes the host to gastrointestinal and metabolic disease, as well as immune system dysfunction. The purpose of this review is to highlight some key concepts pertaining to the interaction between the gut microbiome and host, as well as to illustrate how this interaction influences immune system programming, more specifically, its impact on the development of the immune phenotype characteristic for food allergy. The following discussion will be about the role of the gastrointestinal microbiota, as one of the many factors which contr.. View More»
  DOI: 10.35248/1745-7580.20.16.174

  Abstract HTML PDF