Internal Medicine: Open Access
Open Access

Department of Internal Medicine, University of Oxford, Oxford, United Kingdom

Publications

• Original Research Article   
  In Vitro Anticancer Activity of Native and Modified Black Rice Flour against Colon Cancer Cell Line
  Author(s): Rebecca Webster*
  
  Pigmented rice such as black rice is known for its health-promoting effects and functional activities, owing to the high contents of flavonoids, phenolic compounds, anthocyanins and dietary fiber. Being as a functional food source, black rice provides potential benefit in the prevention of cancer. In this study the modification techniques applied for the preparation of sample were enzymatic modification and heat moisture treatment, with the objective to evaluate cytotoxicity of native and dual modified black rice flour against Human Colorectal Adenocarcinoma cell line (HCT116) and Mouse embryo fibroblast cell line (3T3-L1) by using the MTT assay. In this study, the IC50 of NBRF and DMBRF were 255.78 μg/mL and 340.85 μg/mL, respectively. The result confirms that the NBRF having significant cytotoxic and anti-cancer potential against Human colon cancer cells. Also the IC50 Value o.. View More»
  DOI: 10.35248/2165-8048.22.12.359

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