Journal of Physical Chemistry & Biophysics
Open Access
ISSN: 2161-0398
ISSN: 2161-0398
Department of Medicine and Pharmacy of Tangier, Biophysic Laboratory, Abdelmalek Essaâdi University, Tangier, Morocco
Research
Hyaluronic Acid: Elucidating its Penetration and Effect through the Hair Fibre Using Confocal Raman Spectroscopy and Biometric Techniques for a Set of Cosmetic Benefits
Author(s): Boira Cloe*, Essendoubi Mohammed, Meunier Marie, Lambert Carole, Auriol Daniel, Manfait Michel, Piot Olivier, Scandolera Amandine and Reynaud Romain
Background: Hyaluronic Acid (HA) is well known in the cosmetic industry for its hydrating properties linked to its interaction with keratin in the stratum corneum. Hair is also mainly composed of keratin, but no evidence of penetration and interaction of HA in hair has been established yet due to a lack of appropriate methods.
Methods: Confocal Raman Spectroscopy was used to track HA penetration in hair fibres. Human hair was either UV-irradiated or left untreated before being washed with various shampoo formulations. Low-Molecular Weight hyaluronic acid (LMW at 1% w/v), High-Molecular Weight HA (HMW at 1% w/v), and an optimized blend of low-and high-molecular weight HA (HA-Blend at 1% w/v) were used. The benefits of HA for cosmetic application has been then evaluated at the ex vivo level regarding smoothing, reparative and hydrating propert.. View More»
DOI:
10.35248/2161-0398.24.14.373