Medicinal & Aromatic Plants
Open Access
ISSN: 2167-0412
ISSN: 2167-0412
Department of Human Physiology, College of Medicine, University of Nigeria, Enugu Campus, Enugu State, Nigeria
Research Article
Gastroprotective Effect of Gnetum africanum Ethanolic Extract on Acetic acid induced Peptic Ulcer on Adult Wistar Rats
Author(s): Ugwu Sandrai, Celestine Ani*, Choice Nworgu, Pamela Anyaeji, Ugwu Princewill, Nnamdi Ejim and Nwachukwu Daniel
Peptic ulcer disease also known as stomach ulcer is a break in the lining of the stomach, first part of the small< intestine or occasionally the lower esophagus. Twenty five Wistar rats of both sexes weighing between 180-250 grams< were purchased, housed in metallic cages and maintained under standard environmental conditions at 27 ± 0.13°C at< 12 hr light/dark cycle and relative humidity of 29 ± 0.22%. They were allowed to acclimatize for one week (7 days)< and were fed on standard rodent diet and have free access to drinking water. However, they were divided into five< groups of five rats per group, labeled A to E. Group A: served as Normal control and received normal feed and< distilled water ad libitium Group B: induced with ulcer and left untreated) Groups C, D and E were induced with< ulcer and treated with 20 mg/kg Omeprazole 200 .. View More»
DOI:
10.35248/2167-0412.20.9.354