Medicinal & Aromatic Plants
Open Access
ISSN: 2167-0412
ISSN: 2167-0412
Instituto de QuÃmica Aplicada, Universidad del Papaloapan, Tuxtepec, Oaxaca, Mexico
Review Article
Hepato-Protective Effect from Natural Compounds, Biological Products and Medicinal Plant Extracts on Antitubercular Drug-Induced Liver Injuries: A Systematic Review
Author(s): Oscar Abelardo Ramírez-Marroquín and María Adelina Jiménez-Arellanes*
Tuberculosis is mainly treated with rifampicin, pyrazinamide, isoniazide, ethambutol and/or streptomycin; however, the first three cause hepato- and nephro-toxicity, then the patient abandons therapy. This cause contributes to the failure of the treatment and favors the appearance of drug-resistant strains. Currently, alternatives are being sought to counteract this hepatic-damage, and medicinal plants, natural compounds and/or biological products are of great interest. In this manuscript we describe current data on the hepato-protective effect from extracts of medicinal plants, compounds isolated from them and biological products that protect against liver damage caused by antitubercular (anti-TB) drugs caused by therapy in patients with tuberculosis (TB).
The main consulted databases were: PubMed, Worldwidescience.org, and Scopus, including records between 2000 and 2018 years.. View More»
DOI:
10.35248/2167-0412.19.8.339