Department of Biomedical Engineering, Federal University of Technology, Owerri, Nigeria
Research Article
In-vitro Antidiabetic Assessment of Bioactive Phytochemicals in Locally used Mango and Soursop Leaves
Author(s): Okafor Sixtus Amarachukwu*, Ogbonna Churchill Chisom, Iwuji Samuel Chidi, Ndubuka Gideon Ihebuzor Nnanta and Azeez Taofik Oladimeji
Diabetes mellitus is a chronic metabolic disorder that is characterized by prolonged hyperglycemia. Some plant-based
herbal formulations have been reported to lower blood sugar levels and control diabetic complications. Harnessing
the inherent potentials in plants phytochemicals for specific health therapy remains a challenge. In this study,
and using cold maceration and gravimetric methods for extraction, we isolated, identified and characterized some
bioactive phytochemicals in Mangifera indica (mango leaf) and Annona muricata (soursop leaf). The phytochemicals
were further screened and analysed using qualitative and quantitative techniques. The results of the both samples
revealed the presence of alkaloids, flavonoids, tannins, phenols, terpenoids and saponins with 15.62% flavonoids
and 20.50% saponin yield respectively for Mango Leaf (MGL) an.. View More»
DOI:
10.35248/JPR.23.7.174