Journal of Thyroid Disorders & Therapy
Open Access
ISSN: 2167-7948
ISSN: 2167-7948
Department of Ophthalmology, Sheikh Shakhbout Medical City, Abu Dhabi, United Arab Emirates
Case Report
Teprotumumab's Efficacy for Recurrent Severe Thyroid Eye Disease Post-Tocilizumab and Steroid Therapy
Author(s): Habibullah Eatamadi*, Ohood Almazrouie and Noora AlQattan
Background/Objective: This case report aims to discuss the treatment journey of a patient with increasing thyroid eye disease-related proptosis, who has responded teprotumumab after failre with other available treatment modalities.
Case presentation: The patient was initially seen and diagnosed elsewhere with IGG4-related orbital inflammation and treated with systemic steroids. Later, he became hyperthyroid and his orbital inflammation worsened. Systemic steroids helped the inflammation slightly, but as his condition worsened, he received a cycle of 4 doses of tocilizumab, followed by another cycle of 4 doses of tocilizumab. After a prolonged period of stability, he underwent bilateral rehabilitative lateral orbital wall decompression. Unfortunately, the patient's condition relapsed again. The patient commenced an eight-dose course of te.. View More»