Journal of Applied Pharmacy

Journal of Applied Pharmacy
Open Access

ISSN: 1920-4159

Muhammad Zubair

Department of Pharmacy, Comsats University, Abbotabad, Pakistan

  • Research Article   
    Qualitative Studies on Anti-diabetic Activity of Corchorus depressus
    Author(s): Irum Latif, Riffat Latif*, Iftikhar Khan, Maida Minahil Mushtaq, Muhammad Zubair, Qurat-ul Ain and Rizwan Khalid

    Folklore herbal practioners of Cholistan desert claim Corchorus depressus Linn. (Tiliaceae) treat diabetes pain, fever, gonorrhea, treachery troubles, general weakness and sexual dysfunction. The aim of this study was to isolate α-glucosidase and anti-urease inhibitors and to check the α-glucosidase and anti-urease seasonal in three different time periods. In vitro α-glucosidase and anti-urease assays were carried out and in vivo anti-diabetic activity of Corchorus depressus Linn. Was studied on alloxan induced diabetic rats to show its traditional use. The fractions CD-13, CD-14, CD-15 and CD-20 showed 4.31 ± 0.07, 6.32 ± 0.08, 15.37 ± 0.13 and 12.42 ± 0.13 μg/mL with respect to Acarbose with IC50 37.38 ± 0.12 μM. The fraction CD-M7 and CD-J9 extracts were found active agai.. Read More»

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