Journal of Clinical & Experimental Dermatology Research
Open Access
ISSN: 2155-9554
ISSN: 2155-9554
Department of Skin and Venereal Diseases, Pt. J.N.M Medical College, Raipur, Chhattisgarh, India
Research Article
Low Antioxidant Reserve in First Degree Relatives of Vitiligo Patients
Author(s): Yogita Rajput*, Diksha Mahilang, Akanksha Yadav, Kiran Dhruve, Mritunjay Kumar Singh, Vinod Koshley, Jagannath Pal and Pramod Kumar Nigam
Background: Vitiligo is a chronic autoimmune skin condition characterized by the loss of melanocytes leading to a white patch on the skin. Oxidative stress is a significant key factor in the destruction of melanocytes however antioxidants help neutralize free radicals, which can damage cells and contribute to oxidative stress.
Aims: Our study explored how the role of demographics, lifestyle factors and total antioxidant reserves may interplay in the disease outcome of vitiligo. In this pilot study, we evaluated the total antioxidant reserve in spectrums of vitiligo patients, their first-degree family members and independent healthy individuals.
Methods: A total of 150 Indian study participants were recruited. Venous blood was collected from 59 Vitiligo Patients (VP), their corresponding 59 paired family members (VH.. View More»