Journal of Drug Metabolism & Toxicology
Open Access

Clinical Pharmacy Department, Hamad Medical Corporation, Rumailah Hospital, Doha, Qatar

Publications

• Case Series   
  Successful Clonidine withdrawal in patients receiving Cardio-selective Beta - blockers and Beta-Blockers with Alpha-Blocking Activity
  Author(s): Mostafa Ibrahim ElAwady*, Wasim Akram, Mohamed Sherbash, Noorudeen Kaladi Kunnunmal and Hanadi Al Hamad
  
  Introduction: Clonidine U.S. prescribing information recommends discontinuation of beta blockers several days prior to clonidine withdrawal to reduce the risk of rebound hypertension. In the three cases clonidine was successfully stopped while the patients were receiving Bisoprolol, Carvedilol and Labetalol without rebound hypertension in two months follow up period. Methods: Three cases developed Clonidine induced urinary retention, and it was needed to stop it, but the three cases were receiving Labetalol, Carvedilol and Bisoprolol, so it was decided by multidisciplinary team to stop the Clonidine and as the patients’ heart rate was on the higher side, so it was decided to continue on the beta blockers, continue on the other antihypertensive medications, and follow up the patients for rebound hypertension. Results: .. View More»
  DOI: 10.35248/2157-7609.20.11.244

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