Advanced Techniques in Biology & Medicine

Advanced Techniques in Biology & Medicine
Open Access

ISSN: 2379-1764

+12 184512974

Mingming Zhen

Beijing National Laboratory for Molecular Sciences, Key Laboratory of Molecular Nanostructure and Na, Institute of Chemistry, Chinese Academy of Sciences, University of Chinese Academy of Sciences, China

Publications
  • Mini Review   
    Antineoplastic Activities of Functionalized [email protected] Nanomaterials via Targeting Tumor Vasculature
    Author(s): Xue Li, Mingming Zhen and Chunru Wang*

    It is certain that tumor vasculature plays a crucial role in tumor growth and metastasis with unique physiological features. Up to date, rational design of tumor therapeutics targeting tumor blood vessels has become a consensus strategy. However, the current small molecular anti-vascular drugs are always accompanied by toxicity or side effects. It is still necessary to develop novel medication with high efficacy and low toxicity. Gadofullerene ([email protected]), a novel star material, has been exploited in many different biomedical fields after functionalized. Specially, the highly efficient antitumor effects of functionalized [email protected] were explored extensively by suppressing tumor angiogenesis or cutting off the existing tumor vasculature under radiofrequency (RF) irradiation. And studies demonstrated that no detectable toxicity was observed with functionalized [email protected] Read More»

    Abstract HTML PDF

Top