Journal of Clinical & Experimental Dermatology Research
Open Access
ISSN: 2155-9554
ISSN: 2155-9554
School of Pharmacy and Biomolecular Sciences, Liverpool John Moores University, Liverpool, UK
Research Article
A Double Blinded, Randomized, Controlled Split-Face Study to Investigate the
Efficacy of a Tailor-made Anti-Ageing Skin Care Regimen Adapted to a Genetic
Skin Ageing Risk Profile
Author(s): Barbara Geusens, Liliana Rodrigues, Rita Matias, Bárbera Tavares*, Ana Luísa Fonseca, Ana Margarida Silva, Patrícia Oliveira, Marta de Oliveira Ferreira, Dea Zhilivoda and Géraldine Lagast
Background: Available data suggests that the manifestation of aging has a strong genetic basis, which can modify an
individual ‘ s susceptibility to specific skin aging signs. Proteins such as matrix metalloproteinases, aquaporins,
filaggrin, superoxide dismutase and glutathione peroxidase have specific roles. Their encoding genes present single
nucleotide polymorphisms resulting in different responses to skin aging for elasticity, hydration, barrier function and
wrinkles.
Aim: This study aimed to investigate the anti-ageing and anti-oxidant efficacy of a skin care regimen designed to
address the specific needs of a certain genetic risk profile: high risk for collagen breakdown, medium risk for antioxidant
production and low risk for dehydration and impaired barrier function.
Methods: DN.. View More»
DOI:
10.35248/2155-9554.20.11.527