Journal of Clinical & Experimental Dermatology Research
Open Access

MD, Medica Plus Dermatology Clinic, Via Caduti in Guerra 101, Modena, Italy

Publications

• Research   
  Efficacy of Single Day-Light Photodynamic Therapy Session with Aminolevulinic Acid 5% Thermosetting Gel with a Penetration-Empowering Facial Mask in the Treatment of Severe Actinic Damage of the Face and Scalp
  Author(s): Mario Puviani* and Massimo Milani
  
  Introduction: Photodynamic therapy (PDT) is an effective treatment of actinic keratosis (AK) and severe photo aging. Day-light PDT (DL-PDT) is considered an alternative of C-PDT with similar efficacy but with significantly lower procedure-associated pain. A new formulation of ALA at “low” concentration (5%) in a thermosetting gel is available for C-PDT or DL-PDT. When used for PDT the incubation time of this gel is in general 2-2.5 hours. This formulation with high content of water could be feasible for application with penetration-empowering dual mask which could optimize and speed-up the penetration of the active compound through the skin. This mask device comes in two layers. The first layer is wet and in contact with the applied gel. The second layer, which is dry and overlaid on the first, allows the key ingredients to penetrate the stratum-corneum utilizing a micro-c.. View More»
  DOI: 10.35248/2155-9554.19.10.502

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