Journal of Clinical & Experimental Dermatology Research

Journal of Clinical & Experimental Dermatology Research
Open Access

ISSN: 2155-9554

+44 1478 350008

Mario Puviani

Medica Plus Dermatology Service Modena, Italy

  • Research Article   
    Anti-Wrinkle Efficacy of a Melatonin-Based Eye Contour Balm: An Antera 3D Prospective 2-Month Pilot Trial
    Author(s): Mario Puviani, Klause Eisendle and Massimo Milani*

    Aim: A new eye-contour balm product containing melatnin 0.1%, Butyrospermum Parkii (Shea) butter, a tetrapeptide and hyaluronic acid has been recently developed. So far, no objective data are available regarding the anti-wrinkle effect of topical melatonin in the eye contour area. We performed an open, prospective, 2-month, trial in 20 women (mean age 52 years) with mild-to-moderate wrinkle in the eye-contour area. Subjects and methods: Participating subjects were instructed to apply a melatonin-based eye contour balm (MECB) twice daily (morning and evening). An Antera 3D evaluation of fine wrinkle volume and skin roughness of the crow’s feet area was performed at baseline and after 2 months. The software of the device automatically calculated the roughness index (a parameter linked to fine wrinkles) expressed in mm. Primary outcome was t.. View More»
    DOI: 10.35248/2155-9554.20.11.534

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