ISSN: 2155-9554
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Department of Dermatology, Out-patient Service, Perugia, Italy
Research Article
Clinical Efficacy, Cosmetic Acceptability, and Local Tolerability of a New Formulation of Topical 5% Minoxidil without Propylene glycol: A 6-month,
Multicentre, Real-life, Prospective, Assessor-Blinded Study in 196 Subjects with Hair Loss. The “NOMINAL” Trial
Author(s): Laura Alessi, Luigi Pisano, Fabrizio Presta, Nicolò Rivetti, Elena Saccani, Marco Tomassini, Sonia Torti, Fabrizio Vaira, Giovanni Zanframundo, Mario Puviani, Klause Eisendle, Paola Nappa, Stefania Farina, Maria Catena Aloisi, Valentina Amadu, Alex Arena, Ylenia Balice, Stefania Bano, Stefania Barruscotti, Annunziata Bartolotta, Silvia Bondino, Arianna Corsini, DonatoDi Nunno and Massimo Milani*
Background and trial objectives: A new propylene glycol (PG)-free 5% minoxidil (PG-Free-Mnx) lotion has been recently commercialized. Clinical efficacy and local tolerability have been, so far, documented in a limited number of patients. The aim of this study was to evaluate the clinical efficacy, cosmetic acceptability, and local tolerability of 6-month application of this new PG-Free Mnx lotion in a real-life situation.
Materials and methods: The NOMINAL (NO-PG MINoxidil reAL life study) trial was performed in 22 out-patients Italian dermatology clinics. A total of 196 subjects of both sexes with a diagnosis of AGA/FAGA were enrolled in the trial, after their written informed consent. PG-Free-Mnx lotion was applied 1 ml twice daily for 6 months. Clinical efficacy was evaluated in an open fashion in all the enrolled subjects with a 5-grade .. View More»
DOI:
10.35248/2155-9554.21.12.566