Internal Medicine: Open Access
Open Access

Department of Internal Medicine, Consultant KFS General Hospital, Kafr Elsheikh, Egypt

Publications

• Research Article   
  Autologous Peripheral Blood Mononuclear Cells can Lead to Pancreatic Beta Cell Regeneration
  Author(s): Mahmoud Younis*
  
  Introduction: Type-1 diabetes (T1D) is a disease that leads to pancreatic beta cells death, resulting in complete insulin loss. T1D occurs as a result of autoimmunity which takes insulin producing β cells as a target and is considered as a metabolic disorder causing hyperglycemia resulting from a serious loss of endogenous insulin roduction. Using cadaveric islets as a replacement therapy was done to reverse diabetes. Many various progenitor cell types have been found in the peripheral blood mononuclear cell (PBMC) fraction denoting hose PBMCs may have the ability to differentiate into many mature functional cell types in certain microenvironments. It is settled that circulating peripheral blood mononuclear cells (PBMC) contain germinal cell population which can share in the regeneration of tissues in different organs. Materials and Me.. View More»
  DOI: 10.35248/2165-8048.19.9.305

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