Bipolar Disorder: Open Access
Open Access

Institute of Mental Health, Buangkok Green Medical Park, Singapore

Publications

• Case Report   
  Case Report: Sodium Valproate-Induced Neutropenia in a Patient with Bipolar Disorder
  Author(s): Rajagopalan Arvind*, Lim Shuli, Chan Christopher Yi Wen, Mok Yee Ming and Chandwani Nisha
  
  Background: There are sporadic case-reports suggesting an association between sodium valproate and neutropenia, though the majority of these are in cases of paediatrics and epilepsy. There are a few cases of psychiatric patients developing neutropenia after newly being started on sodium valproate. We present a patient, previously on long-term sodium valproate therapy, who developed neutropenia after being restarted on sodium valproate. Case report: A 52-year-old Chinese man with bipolar disorder, previous well on a combination of sodium valproate and risperidone, was re-admitted for a manic relapse after a period of non-compliance. He developed neutropenia that coincided with increases in sodium valproate dose, and only resolved upon discontinuation of sodium valproate, despite continued increases in risperidone dose. Other investigations fo.. View More»
  DOI: 10.35248/2472-1077.22.8.166

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