Endocrinology & Metabolic Syndrome
Open Access
ISSN: 2161-1017
ISSN: 2161-1017
Department of Traditional Chinese Medicine, University of Traditional Chinese Medicine, Nanchang 330006, Jiangxi, China
Research Article
Effects of Suspended Moxibustion on the Expression of MR, GR and 11β-HSD1 in Hippocampus of Aged Rats
Author(s): You-jiang Min, Hai-hua Yao*, Li Wang, Li-hong Cheng and En-si Hong
Background and aim: According to TCM theory, the kidney-yang is the basis of human functional activities, and the elderly will appear insufficient kidney-yang. Moxibustion is an effective treatment for KYDS, but the exact mechanism remains to be fully elucidated. This research aims to investigate the effects of moxibustion on the hippocampal-HPA axis in aged rats and to elucidate the possible molecular mechanisms.
Method: Thirty-six old male rats were randomly divided into Old Rats Control Group (ORC), moxibustion group (moxi) and Carbenoxolone Group (CBX), and 12 adult rats were included in the young rats control group (YRC), with 12 rats in each group. Rats in the moxi group were received moxibustion and rats in the CBX group were received CBX injection. After treatment, the serum levels of CORT, ACTH and CRH, and the expressions of MR, GR.. View More»
DOI:
10.35248/2161-1017-22.11.367